The CR-60 panel is a set of 59 human cancer cell lines derived from diverse tissues; brain, blood and bone marrow, breast, colon, kidney, lung, ovary, prostate and skin. Since 1992, researchers from across the world have subjected these cell lines to a battery of experiments including extensive pharmacological characterization by treatment with over 100,000 chemical compounds, chromosome karyotyping and gene expression analysis. Within the 59 lines that make up the CR-60 set there are three pairs of lines with high identity to each other (NCI-ADR- RES/OVCAR-8, M14/MDA-MB-435 and SNB19/U251) suggesting the members of each pair share a common source.

* The CR-60 panel comprises the following tumor cell lines:

Breast MCF7 MDA-MB-231 HS 578T BT-549 T-47D NCI-H322M NCI-H460 NCI-H522 Colon COLO 205 HCC-2998 HCT-116 HCT-15 HT29 KM12 SW-620

Melanoma LOX IMVI MALME-3M M14 MDA-MB-435 SK-MEL-2 SK-MEL-28 SK-MEL-5 UACC-257 UACC-62 Ovarian IGR-OV1 OVCAR-3 OVCAR-4 OVCAR-5 OVCAR-8 NCI/ADR-RES SK-OV-3

CNS SF-268 SF-295 SF-539 SNB-19 SNB-75 U251 Leukemia CCRF-CEM HL60 K562 MOLT-4 RPMI-8226 SR Prostate PC-3 DU-145

Non-small cell Lung A549 EKVX HOP-62 HOP-92 NCI-H226 NCI-H23 Renal 786-D A498 ACHN CAKI-1 RXF 393 SN12C TK-10 UO-31

* Four levels of service available

* Results in three weeks. (sample results report)